|Description||GCP4 rabbit polyclonal|
|Protein full name||Gamma-tubulin complex component 4|
|Synonyms||GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76, TUBGCP4, 76P, GCP4|
|Immunogen||KLH conjugated Synthetic peptide
corresponding to Mouse GCP4
|Predicted MW.||76 kDa|
|Observed MW.||76 kDa|
|WB||Humant||1: 500-1: 800||MCF7, HepG2, HCT116|
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy.
Western blot analysis of GCP4 (GB111447)
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.|
|Storage Buffer||PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.|
NOTE: This product is intended for research only.